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Swine flu jab narcolepsy risk is very small
Conclusion This study confirms that the Pandemrix vaccine against swine flu is associated with a very small risk of narcolepsy in children and young people. As the authors point out, this risk may have been overestimated if children with narcolepsy who had been vaccinated were more rapidly referred than others because of increased awareness of the link. The methods used were practical for a rapid assessment of risk, but as this was essentially a case series analysis they are limited by a number of factors: The rates calculated are dependent on the accurate diagnosis and identification of the cases of narcolepsy. By usin...
Source: NHS News Feed - February 27, 2013 Category: Consumer Health News Tags: Medication Medical practice Swine flu Source Type: news

Development of a Reproducible Swine Model of Chronic Ischemic Mitral Regurgitation: Lessons Learned.
CONCLUSION: A reproducible percutaneous model of severe IMR in swine is feasible with a guided anesthetic and peri-operative approach. This model can serve as a platform to better understand the mechanism of IMR and subsequently to test novel repair techniques. PMID: 32553769 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - June 14, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Pasrija C, Quinn RW, Alkhatib H, Tran D, Bernstein D, Rice M, Kotloff E, Morales D, D'Ambra MN, Vesely M, Gammie JS Tags: Ann Thorac Surg Source Type: research

Viruses, Vol. 15, Pages 1925: Bridging the Gap: Can COVID-19 Research Help Combat African Swine Fever?
hanarat African swine fever (ASF) is a highly contagious and economically devastating disease affecting domestic pigs and wild boar, caused by African swine fever virus (ASFV). Despite being harmless to humans, ASF poses significant challenges to the swine industry, due to sudden losses and trade restrictions. The ongoing COVID-19 pandemic has spurred an unparalleled global research effort, yielding remarkable advancements across scientific disciplines. In this review, we explore the potential technological spillover from COVID-19 research into ASF. Specifically, we assess the applicability of the diagnostic tools, vac...
Source: Viruses - September 15, 2023 Category: Virology Authors: Danaya Pakotiprapha Sakonwan Kuhaudomlarp Ruchanok Tinikul Sittinan Chanarat Tags: Review Source Type: research

Swine flu: lessons we need to learn from our global experience.
Authors: Collignon P Abstract There are important lessons to be learnt from the recent 'Swine Flu' pandemic. Before we call it a pandemic, we need to have appropriate trigger points that involve not only the spread of the virus but also its level of virulence. This was not done for H1N1 (swine flu). We need to ensure that we improve the techniques used in trying to decrease the spread of infection-both in the community and within our hospitals. This means improved infection control and hygiene, and the use of masks, alcohol hand rubs and so on. We also need to have a different approach to vaccines. Effective vaccin...
Source: Emerging Health Threats Journal - December 2, 2014 Category: Global & Universal Tags: Emerg Health Threats J Source Type: research

African swine fever: an unprecedented disaster and challenge to China
ConclusionsASF is an unprecedented disaster and challenge to the Chinese swine industry. It will be a formidable and protracted campaign to control ASF in China, which requires joint participation and coordination of stakeholders and agencies at different levels.
Source: Infectious Diseases of Poverty - October 26, 2018 Category: Infectious Diseases Source Type: research

Study of Profile of Swine Flu Cases Admitted in Tertiary Care Hospital: Lessons Learned!
Introduction Swine flu is caused by a novel strain of H1N1 influenza A virus that evolved by genetic assortment. The global pandemic affected India in May 2009. Sporadic cases continue to occur and cause significant morbidity and mortality. Aim To study the clinical profile, laboratory parameters, and outcome of the confirmed cases of swine flu. Methods This was a retrospective study involving confirmed swine flu cases admitted with category B2 and C symptoms from February to September 2019 in Tata Main Hospital. Their case records were analyzed for demographic characteristics, clinical features, treatmen...
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Original Articles Source Type: research

The MHC-characterized Miniature Swine: Lessons Learned From a 40-Year Experience in Transplantation
Over the last 40 y, a specialized herd of miniature swine has been intentionally bred to develop lines of animals homozygous for the swine major histocompatibility complex (MHC), which have facilitated transplantation studies across reproducible MHC and minor antigen mismatch barriers. These MHC-characterized miniature swine (Mc-MS) have been used for the study of novel surgical techniques, various approaches to tolerance induction of solid organ and vascularized composite allografts, as well as studies of the immunobiology of allografts and xenografts. Mc-MS possess characteristics that are highly advantageous to these st...
Source: Transplantation - May 1, 2022 Category: Transplant Surgery Tags: Reviews Source Type: research

Next Phase of NIH Preprint Pilot Launching Soon
Last month, the National Library of Medicine (NLM)announced plans to extend its NIH Preprint Pilot in PubMed Central (PMC) and PubMed beyond COVID-19 to encompass all preprints reporting on NIH-funded research. The second phase of the pilot, launching later this month, will include preprints supported by an NIH award, contract, or intramural program and posted to aneligible preprint server on or after January 1, 2023.In preparation for the launch of this second phase, we have updated PMC and PubMed site features to help users of these databases incorporate the increased volume of preprints into their discovery workflows. S...
Source: PubMed Central News - January 10, 2023 Category: Databases & Libraries Source Type: news

Second Phase of the NIH Preprint Pilot Launched
Today, we are pleased to announce the launch of the second phase of the NIH Preprint Pilot with the addition of more than 700 new preprint records to PubMed Central (PMC) and PubMed. This second phase expands the scope of the Pilot to include preprints resulting from all NIH-funded research. Eligible preprints are those acknowledging direct support of an NIH award or authored by NIH staff and posted to bioRxiv, medRxiv, arXiv, or Research Square, on or after January 1, 2023. NLM will automatically include the full text of the preprint (as license terms allow) and associated citation information in PMC and PubMed, respectiv...
Source: PubMed Central News - January 30, 2023 Category: Databases & Libraries Source Type: news

First outbreak with chimeric swine enteric coronavirus (SeCoV) on pig farms in Slovakia - lessons to learn.
This report describes the first disease outbreak caused by chimeric swine enteric coronavirus (SeCoV) on two pig farms in Slovakia in early 2015. The infection was introduced by import of two breeding boars which were placed in provisional quarantine in a unit not strictly separated from other healthy pigs in the same building. Subsequently, loss of appetite and diarrhoea were observed in both boars during the first three days in the isolation unit. The infection gradually spread to the farrowing area and throughout the farm in two weeks and later to another nearby farm. Yellow watery diarrhoea accompanied by dehydration a...
Source: Acta Veterinaria Hungarica - September 1, 2018 Category: Veterinary Research Authors: Mandelik R, Sarvas M, Jackova A, Salamunova S, Novotny J, Vilcek S Tags: Acta Vet Hung Source Type: research

Pathogenesis of African swine fever in domestic pigs and European wild boar - lessons learned from recent animal trials.
Abstract Over the last decade, African swine fever (ASF) has changed from an exotic disease of Sub-Saharan Africa to a considerable and serious threat to pig industry in Central Europe and Asia. With the introduction of genotype II strains into the European Union in 2014, the disease has apparently found a fertile breeding ground in the abundant wild boar population. Upon infection with highly virulent ASF virus (ASFV), a haemorrhagic fever like illness with high lethality is seen in naïve domestic pigs and wild boar. Despite intensive research, virulence factors, host-virus interactions and pathogenesis are stil...
Source: Virus Research - April 2, 2019 Category: Virology Authors: Pikalo J, Zani L, Hühr J, Beer M, Blome S Tags: Virus Res Source Type: research

On RSS Readers, Divorce and Marriage
In just a few days, Google Reader will be history.  I've used it to create over 18,000 Tweets, so yes, I will miss Google Reader.  The end has pushed me into a divorce (or maybe it's just a separation?!) — from Google.  I describe my Google divorce as kind of like when a married couple with children decide to separate … they still have to see their exes for the sake of the kids (and I still have my blogs with Google's Blogger, for now anyway), and it may be a cordial, but not quite blissful separation, but is still necessary.A number of my fellow diabetes blogging peers have already migrated from Google'...
Source: Scott's Web Log - June 28, 2013 Category: Diabetes Authors: Scott S Source Type: blogs

'By failing to prepare you are preparing to fail': lessons from the 2009 H1N1 'swine flu' pandemic
Conclusions: Policy makers should prioritize investment in the skills and expertise required to achieve desired behaviour changes. Audience research should be conducted throughout the planning cycle to inform national communications strategies. This should include insights to inform the segmentation of public audiences, targeting of messages and consideration of content and emotional tone most likely to achieve desired behavioural outcomes.
Source: The European Journal of Public Health - January 23, 2015 Category: Journals (General) Authors: Crosier, A., McVey, D., French, J. Tags: Infectious diseases Source Type: research

Evolution of a Search: The Use of Dynamic Twitter Searches During Superstorm Sandy
Conclusion The most important lesson learned from Superstorm Sandy was the need for a dynamic and flexible monitoring process and strategy to understand and respond quickly to health needs in the areas impacted by Superstorm Sandy. Search strategies should change as frequently as the unfolding event. The inability to adapt to a changing situation ensures stale and stagnant terminology and search results. Twitter lists and Boolean searches should be used together to maximize situational awareness. The most important information comes from the impacted population, whether news, local government or local citizens. These are t...
Source: PLOS Currents Disasters - September 26, 2014 Category: Global & Universal Authors: Sara Harris Smith Source Type: research

Lessons from a systematic literature search on diagnostic DNA methylation biomarkers for colorectal cancer: how to increase research value and decrease research waste
DiscussionThis systematic literature search revealed that major requirements to develop clinically relevant diagnostic CRC DNA methylation markers are often lacking. To avoid the resulting research waste, clinical needs, intended biomarker use and independent validation should be better considered prior to study design. In addition, improved reporting quality would facilitate meta-analysis, thereby increasing level of evidence and enabling clinical translation.PMID:35584320 | DOI:10.14309/ctg.0000000000000499
Source: Clinical Colorectal Cancer - May 18, 2022 Category: Cancer & Oncology Authors: Zheng Feng Cary J G Oberije Alouisa J P van de Wetering Alexander Koch Kim A D Wouters Nathalie Vaes Ad A M Masclee Beatriz Carvalho Gerrit A Meijer Maurice P Zeegers James G Herman Veerle Melotte Manon van Engeland Kim M Smits Source Type: research